CD-1® IGS Mouse Details The original group of Swiss mice that served as progenitors of this stock consisted of two male and seven female albino mice.
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On the donor's Day 17, inject 5 mg Depo-Provera (0.03ml of 150 mg/ml) subcutaneously (scruff the neck, insert the needle between your fingers, then withdraw it slightly before depressing the plunger). The morning of the CD1 foster mother's Day 19, the CD1 foster will give birth. The morning is the best time to foster the pups. Fostering Procedure.
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Development in CD1 Mice with Taconic (TAC) GM Profile Future Directions Differences in gut microbiota (GM) have been shown to modulate many mouse models of disease including colorectal cancer, inflammatory bowel disease, and neurological disorders Little is known about early life mouse GM.
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Litter average: 11.5. Most widely-used outbred mouse. Origin: The Hsd:ICR (CD-1®) mouse model is of Swiss origin and descended from the original two male and seven female albino non-inbred mice, imported by the Rockefeller Institute.
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To test this, we applied selamectin to mdr1‐deficient mdr1a,b−/− knockout mice and wild‐type mice Visit Us at Your Local Southern States These mice may be useful in studying NKT cell immunology; including Th1- and Th2-responses, antiviral and antitumor responses, asthma, various inflammatory responses, autoimmunity and peripheral tolerance In animal.
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The CD-1 Mouse originates from the laboratory of Dr. de Coulon in Lausanne, Switzerland. The mice were derived from two male and seven female albino mice. CD-1 mice were originally imported into the US in 1926 by Dr. Clara Lynch of Rockefeller University. Coat Color: White (albino) Research Applications: General multipurpose model.
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CD1 mice spend more time in the chamber with a stranger mouse than that a novel object, suggesting that their preference is social in nature. Thus, outbred CD1 mice are as appropriate as inbred C57 mice for studying social behavior using either the single or the three-chamber test using a specific acclimation paradigm.
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The metabolism of BPA by CD1 mice liver microsomal and S9 fractions was investigated. Nine metabolites were isolated and characterized using HPLC and mass spectrometry. Many of these metabolites were characterized for the first time in mammals, namely isopropyl-hydroxyphenol (produced by the cleavage of BPA), a bisphenol A glutathione conjugate.
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Rare major histocompatibility complex (MHC) class I-like CD1-specific T cells have been isolated from human blood, but it has not been determined whether these clones are part of a defined subset of CD1-specific T cells selected during T cell development, or whether their recognition of CD1 is a fortuitous cross-reaction. In mice, an entire.
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CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Inorganic arsenic exposure via drinking water has been associ-atedwithcancerandserious injury invarious internal organs, aswell as with peripheral neuropathy and diverse effects in the nervous system. Alterations in memory and attention processes have been reported in.
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The 20H2 monoclonal antibody reacts with mouse CD1d also known as CD1.1. CD1d is a 48 kDa type I membrane glycoprotein and a member of the CD1 family of glycoproteins. CD1d is a non-classical MHC protein with structural homology to class I MHC molecules. CD1d is expressed on the surface of various antigen-presenting cells and is involved in the presentation of non.
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To address this issue, we examined the expression of metabolic enzymes and the regulatory role of DNA methylation in the primary hepatocytes of two mouse strains, CD-1 and C57BL/6. Primary culture of mouse hepatocytes was established using collagen sandwich configuration. Analysis of gene expression of 24 phase I, 18 phase II, and 6 phase III.
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The 20H2 monoclonal antibody reacts with mouse CD1d also known as CD1.1. CD1d is a 48 kDa type I membrane glycoprotein and a member of the CD1 family of glycoproteins. CD1d is a non-classical MHC protein with structural homology to class I MHC molecules. CD1d is expressed on the surface of various antigen-presenting cells and is involved in the presentation of non-peptide glycolipid antigens.
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Using this method, not only the amounts of phospholipids and glycerolipids in each organ/tissue but also the fatty acid compositions were acquired. In order to explore the interspecies specificity of lipid distribution in different organs/tissues, three animal species including CD1 mice, NMRI mice, and Wister rats were used in this systematic.
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CD1d, known as CD1.1 and Ly-38, is a 48 kD type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. In humans, CD1 family consists of group I proteins (CD1a, CD1b, and CD1c), group II (CD1d), and group III (CD1e). But CD1d is the only CD1 molecule has been found in mouse.
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On the donor's Day 17, inject 5 mg Depo-Provera (0.03ml of 150 mg/ml) subcutaneously (scruff the neck, insert the needle between your fingers, then withdraw it slightly before depressing the plunger). The morning of the CD1 foster mother's Day 19, the CD1 foster will give birth. The morning is the best time to foster the pups. Fostering Procedure.
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Incidence of spontaneous neoplastic and nonneoplastic lesions in Charles River CD-1® mice varies with breeding origin. Toxicol Pathol. Toxicol Pathol. 1993 ;21(6): 538 - 541 . doi: 10.1177/019262339302100603.
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The CD1 mouse is a commonly-used outbred strain for general multipurpose studies, but has also been extensively studied in oncology, toxicology, aging, and immunology. Because they are outbred, the genetic profile of these mice is unknown. However, their immune cells (like these CD1 mouse PBMCs) are routinely used in immune-based assays when.
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Abstract. CD-1 is the outbred mouse line most often used in toxicology and carcinogenicity bioassays. A literature survey revealed a relatively high (21.8%) incidence of spontaneous lung tumors in these mice, and a susceptibility to lung tumorigenesis induced by vinyl chloride, styrene or benzene inhalation that is not seen in B6C3F1 or C57BL/6 mice, or in.
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Schematic summary for site-specific ϕC31 integrase-mediated transgenesis via pronuclear injection in mice. A single or three tandem attP sites were knocked into the Hipp11 ( H11) or Rosa26 loci via homologous recombination in ES cells ( Left; for details, see Fig. S1 ). Mice homozygous for one of the modified loci ( H11 is shown as an example.
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CD1. Description. Unloaded CD1 reagents are provided as a negative control for ligand loaded CD1 reagents, and also can be loaded by clients with their choice of ligands. It should be noted that unloaded CD1 molecules have likely bound ligands during expression in 293T cells. Protein. mouse CD1d. Host Species.
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Knockout mice also offer a biological context in which drugs and other therapies can be developed and tested. Many of these mouse models are named after the gene that has been inactivated. For example, the p53 knockout mouse is named after the p53 gene, which codes for a protein that normally suppresses the growth of tumors by arresting cell.
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CD-1® mouse cells are isolated from CD-1® IGS mice purchased from Charles River. CD-1® IGS mice are outbred mice and are derived from a group of non-inbred Swiss albino mice developed at the Centre Anticancereux Romand in Lausanne, Switzerland. They were imported to the US in 1926 and to Charles River in 1959.
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Homozygous mutant mice lack the normal natural killer cell -like T cell subset. Mice homozygous for the <i>Cd1<sup>tm1Gru</sup></i> knock-out mutation are deficient in both the <i>Cd1d1</i> and <i>Cd1d2</i> genes (CD1.1, CD1.2). Homozygous mutant mice lack the normal natural killer cell -like T cell subset. 003814 - CD1[-] Strain Details.
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